In a small mixing bowl, COMBINE yeast and warm water; let STAND until bubbly, about five minutes; ADD buttermilk; SET aside.
In a large mixing bowl, COMBINE dry ingredients--flour, sugar, baking powder, soda, salt.
CUT in shortening until mixture resembles coarse meal.
ADD buttermilk mixture, MIXING with a fork until dry ingredients are moistened.
TURN dough onto a floured surface; KNEAD lightly three or four times.
ROLL dough to 1/2-inch thickness; CUT with a 2 3/4-inch biscuit cutter.
PLACE on lightly greased baking sheets; COVER; let RISE one hour.
BAKE at 425 F until golden brown, about eight to ten minutes
Per Serving (excluding unknown items): 381 Calories; 18g Fat (42.4% calories from fat); 7g Protein; 48g Carbohydrate; 2g Dietary Fiber; 1mg Cholesterol; 483mg Sodium. Exchanges: 2 1/2 Grain(Starch); 0 Lean Meat; 0 Non-Fat Milk; 3 1/2 Fat; 1/2 Other Carbohydrates.