PREHEAT oven to 375.
Over hot water, COMBINE butterscotch chips and butter; STIR until chips are melted and mixture is smooth.
TRANSFER to a large mixing bowl; STIR in graham cracker crumbs and walnuts with a fork until mixture resembles fine crumbs; RESERVE 2 cups crumb mixture for topping.
PRESS remaining mixture into 15 x 10-inch baking pan; BAKE 12 min.
In large mixing bowl, COMBINE cream cheese and sugar; BEAT until creamy.
ADD eggs, one at a time, beating well after each addition; BLEND in flour and vanilla.
POUR evenly over hot baked crust; SPRINKLE with reserved crumb mixture; BAKE 25 minutes.
When completely cool, CUT into bars; CHILL before serving.
Per Serving (excluding unknown items): 1110 Calories; 40g Fat (31.2% calories from fat); 12g Protein; 187g Carbohydrate; 2g Dietary Fiber; 144mg Cholesterol; 354mg Sodium. Exchanges: 1 Grain(Starch); 1 1/2 Lean Meat; 7 1/2 Fat; 11 1/2 Other Carbohydrates.